"...what's inspired the title is, 50 and G-Unit are putting on a sold-out performance somewhere in a fictional Middle Eastern setting. This is where the 'blood on the sand' comes in. They put on the performance; the people are pleased, but the concert promoter stiffs them and doesn't give 50 and G-Unit their payment.
So, of course, 50 isn't going to leave until he gets paid, so he hassles the concert promoter, [saying] if he doesn't come up with the money now, there will be consequences. And instead, the promoter offers him a very valuable gift - something that's valuable to this particular country - a diamond encrusted skull.
So 50 gets the skull, and as he's about to leave this war-torn country, when they're ambushed and the skull is taken. They escape the ambush, but they're without the skull. So 50's motivated to get what belongs to him. So basically, throughout the game, he's trying to track these people down and find out who they are and why he was ambushed."
Woah, national treasures? Skulls that make me think of an episode of Family Guy? A rich billionaire who cannot stand to loose a couple hundred thousand. Weird.
They also mention some of the game modes, such as the drop-in, drop-out cooperative mode (like in Gears of War) where your friend can drop in being either Lloyd Banks, Tony Yayo or DJ Whoo Kid. Unfortunately, they cannot reveal if the only two characters that matter, Eminem and Dr. Dre, are in the game.